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Original Research Article | OPEN ACCESS

Efficacy of artemether-lumfantrine (Co-Artesiane) suspension in the treatment of uncomplicated Plasmodium falciparum malaria among children under 5 years in eastern Sudan

Muntaisr T Salah1, Mohamed . Faroug2, Mamoum M Magzoub2, Ishag . Adam3

1Ribat University, Sudan; 2Kassala University, Sudan,; 3Faculty of Medicine, University of Khartoum, Sudan and The Academy of Medical Sciences and Technology.

For correspondence:-  Ishag Adam   Email: ishagadamm@yahoo.com   Tel:+ 249912168988

Published: 27 June 2006

Citation: Salah MT, Faroug M., Magzoub MM, Adam I.. Efficacy of artemether-lumfantrine (Co-Artesiane) suspension in the treatment of uncomplicated Plasmodium falciparum malaria among children under 5 years in eastern Sudan. Trop J Pharm Res 2006; 5(1):551-555 doi: 10.4314/tjpr.v5i1.5

© 2006 The authors.
This is an Open Access article that uses a funding model which does not charge readers or their institutions for access and distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) and the Budapest Open Access Initiative (http://www.budapestopenaccessinitiative.org/read), which permit unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited..

Abstract

Purpose the aim of the present study was to investigate the efficacy of artemetherlumfantrine (Co-Artesiane®) suspension for the treatment of uncomplicated Plasmodiumfalciparum malaria in children (aged 6-59 months) in Kassala in eastern Sudan.
Method This was a prospective clinical trial where the artemether-lumfantrine (Co-Artesiane®) suspension was given for three days and the patients were followed-up for 28 days.
Results: Forty-eight patients were enrolled in the study and 43 of them completed the 28- days follow-up. Treatment rapidly cleared parasitemia and fever. The overall 28-day cure rate was 100% and no clinical or parasitological failures were observed among these patients. Mild side effects were observed in three (7%) children.
Conclusion: Artemether-lumfantrine (coartem) suspension appears to be efficacious and safe for the treatment of uncomplicated malaria.
 

Keywords: Artemether-lumfantrine, Co-Artesiane, children, falciparum, malaria, Sudan

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